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KMID : 0359920030220030321
Korean Journal of Nephrology
2003 Volume.22 No. 3 p.321 ~ p.325
A case of Postinfectious Glomerulonephritis Following Meningococcal Meningitis
½Å¼ºÃ¶/Shin SC
±èÀ±±¸/¹éÇöÁ¤/ÀÓ¿µÈ¯/¿©È£¸í/±èÀÀÈ£/±èÁ¤¾Æ/À̹æÈÆ/°­¿ìÇå/±è¹ü/Çã¿ì¼º/±è´ëÁß/¿ÀÇÏ¿µ/±Ç±â¿µ/Kim YG/Back HJ/Lim YH/Yeo HM/Kim EH/Kim JA/Lee BH/Kang WH/Kim B/Huh WS/Kim DJ/Oh HY/Kwon GY
Abstract
A 21-year-old male was presented with sudden headache, fever, petechiae and neck sfiffness. The diagosis of meningococcal meningitis was confirmed by examination of cerebrospinal fluid. The clinical symptoms of the illness were improved after treatment of antibiotics. However the patient developed generalized edema, oliguria, azotemia and heavy proteinuria in the recovery phase of illness. Low serum C3 level was also noted. A kidney biopsy was performed and showed the features of postinfectious glomerulonephritis and typical subepithelial humps of electro-microscopic examination. His symptoms and laboratory findings were improved, and C3 level returned to normal range after conservative treatment. We suggest that a complement deficiency should be ruled out in patients of glomerulonephritis developed during the recovery phase of meninggocaccal meningitis. C3 nephritic factor detection and renal biopsy should be carefully considered in the patients.
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